The positive side (and getting technical)

OK. I have now had a chance to look at the results in more detail and…those who know me will know i tend to look on the positive side whenever i can.

The oestrogen is doing very nicely. Actually double what it was before i started the hormone treatment and right at the top of its range. And there are other rather noticeable side-effects, for which i am daily grateful.

So on the whole, a result.

Now here’s where it starts getting techy and may be more interesting to the biochemists – and anyone else transitioning.

A friend, who has been through this all a long time ago, suggests i might need to ask about an increased HRT dose and a GnRH analogue. Huh?

Well: i’ve googled the latter, and it seems to be fairly heavy stuff. Also comes with a health warning about side-effects. So first question to anyone who has tried it is: what does it do and is it worth it?

Second up, which also sounds fairly positive, is that Finasteride, which i understood to be an anti-androgen is not exactly that. Rather, it blocks some specific precursor chemicals: therefore i am not technically taking an anti-androgen and should just ask for one.

No wonder, therefore, that my testosterone levels appear to be stuck!

Again, any thoughts from those who have trodden this path before would be very welcome.

How strange. Before i began to transition, i would read posts from others with just these sort of techy questions and think: surely you don’t need to know all that. And now here i am, as bad – or as good – as they.

Things change. Always.



2 Responses so far »

  1. 1

    Denise Anderson said,

    Okie dokie…

    I’m not sure Jane if you are in the system? ie NHS system etc…

    GnRH analogue are relatively ok, the common 2 are Zoladex (Gosrelin), an injectable pellet, which is quite expensive in terms of PCTs and GPs go ouch as it’s about £136 a shot, the alternative that Dr Seal has been starting to push out on recommendations, but everyone is different so it’s not so widespread is Triptorelin.

    Both do the same thing in knocking your testosterone levels right down, affectively chemically castrating… they don’t give the horrible affects open the liver that pills such as Androcur (cyproterone acetate) do or give you as much depressive affects…

    It tends to be down to your blood tests showing your T levels, if they are still up
    above the female norm then the anti androgens are looked at in terms of helping

    Finesteride doesn’t really benefit as a anti androgen, it blocks the DHT androgen and will help in some way with partial hair regrowth, as well as help with prostrate problems that we still have the potential of 🙂

  2. 2

    Jenny Alto said,

    They gave finasteride to me without question when I asked for it and since I’m doing my best to stay a bloke its general anti-androgenic effects must be minimal. It blocks the action of an enzyme that converts testosterone to a more potent form, causing the prostate to shrink, and hair regrowth as a side-effect.

    One side effect hasn’t happened to me sadly, I’m told that 2% of men given finasteride experience gynaecomastia. Typical, the one patient who would be happy with that effect doesn’t get it!

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